INTERMITTENT DIETARY METHIONINE DEPRIVATION FACILITATES TUMORAL FERROPTOSIS AND SYNERGIZES WITH CHECKPOINT BLOCKADE

Intermittent dietary methionine deprivation facilitates tumoral ferroptosis and synergizes with checkpoint blockade

Abstract Dietary methionine interventions are beneficial to apoptosis-inducing chemotherapy and radiotherapy for cancer, while their effects on ferroptosis-targeting therapy and immunotherapy are unknown.Here we show the length of time methionine deprivation affects tumoral ferroptosis differently.Prolonged methionine deprivation prevents glutathio

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Supporting Holistic Wellbeing for Performing Artists During the COVID-19 Pandemic and Recovery: Study Protocol

The COVID-19 pandemic resulted in the abrupt closure of circus schools, venues, and companies, introducing a myriad of novel stressors.Performers and students must now attempt to maintain their technical, physical, artistic, creative, and cognitive abilities without in-person support from their coaches and must manage the isolation from their train

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Near Infrared Light Triggered Photo/Immuno-Therapy Toward Cancers

Nanomaterials-based phototherapies, mainly including Braces photothermal therapy (PTT), photodynamic therapy (PDT) and photoimmunotherapy (PIT), present high efficacy, minimal invasion and negligible adverse effects in cancer treatment.The integrated phototherapeutic modalities can enhance the efficiency of cancer immunotherapy for clinical applica

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